Indian Institute of Advanced Research (IIAR)


During the year of 2007, I moved my research base to a remote Indian village of Koba in Gujarat. There is a modern biological research institute, which appears rather out of place in the idyllic surroundings. The Indian Institute of Advanced Research was founded in 2006 by Puri Foundation, an NRI*-owned foundation to promote biotech development in India. The campus is located about 10 km south of the city of Gandhinagar, the capital city of Gujarat, and sits on the Sabarmati River. This waterfront location provides the flora and fauna rich in diversity. Monkeys, deer, peacocks, parrots, owls, and butterflies are regularly seen on the campus.

*NRI stands for Non-Resident Indian. Indian citizens emigrated to other countries, or persons of Indian origin residing overseas are usually called NRIs.

Technology Transfer Initiated at IIAR

Identification of CAX Transporter Diversity

Toshiro Shigaki Project - Acacia TreeMy duty at the institute was to initiate new projects in plant science that are both forefront science and relevant to local needs. Since 1999, I have been working on a group of plant transporters called CAX. What it does in the plant cell is that it moves cations into the vacuole. The vacuole can act as a garbage bag in the plant cell, and when the heavy metals are sequestered in it, the cell function is protected from the toxic effects of the metals. This concept makes a practical project because if appropriate plants are engineered by genetic transformation with CAX genes to enhance the metal accumulation in the vacuole, they can be used as biological “sponge” to remove contaminations from soil (phytoremediation).  To identify CAX genes with unique substrate specificity, we initiated the search for new CAXs from local plants. Our search identified two CAX proteins with an extra transmembrane helix insertion (Jain et al., 2009), a truly unique feature that warrants further investigation.

N. Jain, R. Nadgauda, and T. Shigaki. (2009) Mining cation (CAX) transporter diversity for nutrition-enhanced crops and phytoremediation.  International Journal of Integrative Biology 7:22-25.  

DNA Barcoding


DNA Barcoding - Acacia PodsAnother project I initiated was the DNA barcoding of local plants found in the semi-arid state of Gujarat. DNA Barcoding has been successfully used for animals and fungi for some time using the COI (the cytochrome c oxidase subunit 1 mitochondrial region). However, this region has unacceptably low variability as a species identification tool and the research community is looking for alternative regions. Here, we are using several candidate DNA markers that have been proposed by international consortia and studying the diversity of local acacia species. Acacias are beautiful trees very well adapted in the dry and hot Indian climate, and provide medicines, fodder, and construction materials to locals. The IIAR campus is full of acacia trees, mainly Acacia tortilis and Acacia nilotica. In the long term, we also plan to barcode other economically important plants, such as medicinal and aromatic herbs.
 

IIAR Surroundings


IIAR - Puri Foundation Neel Gai near IIAR Campus Beautiful Rainbow - IIAR Campus

Although rich in natural beauty, modern amenities are rare around the campus. To buy vegetables and fruits, we have to walk about half an hour to the nearby Raisan village, or one hour to Koba village, which is bigger than Raisan. For other necessities, we have to travel to Gandhinagar or Ahmedabad. Since 2007, the IIAR campus area has seen a rapid development, including the establishment of Pandit Deendayal Petroleum Univeristy by the Reliance Group. The area is expected to be one of the major research centers in Gujarat.
 
Indroda National ParkGandhinagar is the capital city of Gujarat, and one of the few planned cities in India.  Gandhinagar is probably the greenest city of all Indian cities I have ever visited.  Despite its image as an administrative center, Gandhinagar has its share of tourist attractions, including a unique dinosaur park (Indroda Nature Park) which boasts its life-size dinosaur statues and real dinosaur egg fossils. The famous Akshardham Temple is also located in the city. One of the most famous Indian stepwells, Adalaj ni Vav is located just south of the city.


AhmedabadAhmedabad is one of the seven biggest cities in India, and offers a wide range of shopping and entertainment opportunities. Some of the local attractions are Sidi Sayed Mosque, Sarkhej Roza, and the Swaminarayan Temple. Sidi Sayed Mosque has ten screen windows (jalis), with beautiful carved images of trees, which is generally regarded to represent the city. In 2009, Bus Rapid Transit System (BRTS) was started to ease the traffic jam. The BRTS buses run on a dedicated bus lane and the system works pretty much like a train line. Last, but not the least, Ahmedabad is scorchingly hot in the summer with the maximum temperatures reaching 45°C, so be prepared if you plan to visit the city in the summer months.